The monument to the 27th Indiana Infantry Regiment at Antietam is on the north side of Cornfield Avenue. (Cornfield Avenue East tour map)
The regiment is also honored by a monument on the Chancellorsville battlefield and a monument at Gettysburg.
The 27th Indiana Infantry at Antietam
Colonel Silas Cosgrove commanded the regiment at Antietam by. It lost 41 men killed and 168 wounded out of 443 men engaged during intense fighting in the Cornfield.
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Attached to the 3rd Brigade, 1st Division, 12th Corps, Army of the Potomac
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About the monument
The monument is made from Barre, Vermont Granite. All the Indiana monuments at Antietam were designed by sculptor John K. Lowe and manufactured by the J.N. Forbes Company of Chambersburg, Pennsylvania. They were dedicated on the 48th anniversary of the battle on September 17, 1910.
Text from the monument:
THE 27th INDIANA INFANTRY
3rd Brigade, 1st Division, 12th Army Corps
Col. Silas Colgrove, Commanding,
Was engaged with the enemy 400 yards
north of this marker. Sept. 17, 1862.
Number engaged 440.
Killed and wounded 209. 
Location of the monument
The monument to the 27th Indiana Infantry is north of Sharpsburg on the north side of Cornfield Avenue 350 yards east of the old Hagerstown Pike, also known as Dunker Church Road. (39°28’52.1″N 77°44’40.9″W)